A list of aircraft operators that have that have suffered an accident, serious incident or hijacking. The list may also contain defunct airlines or airlines that in the meantime have changed their name or have merged.

Airlines:
Air Class Líneas Aéreas
ALAS - Atlantida Linea Aérea Sudamericana
ARCO - Aerolineas Colonia
CAUSA - Compañia Aeronautica Uruguaya SA
PLUNA

Military:
Aviación Naval Uruguaya
Fuerza Aérea Uruguaya - FAU
Transporte Aéreo Militar Uruguayo - TAMU

Private:
Juan Adorisio Naschez